Lawson study finds high rate of mortality among those with COVID-19-renal failure   


Variants of COVID-19

Viruses, including COVID-19, are continually changing due to mutation, as seen by the Delta and Omicron variants, and new COVID-19 variations are predicted to emerge. Even if completely vaccinated, those with renal illness at any stage and kidney transplant patients may not have as much protection against COVID-19. For persons who are not completely vaccinated, the NKF advises following the same CDC precautions, which include wearing a mask in public indoor settings.

According to the Lawson research, people with COVID-19-induced acute renal failure had a significant fatality risk. ?

Researchers at the Lawson Health Research Institute in London discovered a greater likelihood of death among Ontarians who experienced acute renal damage as a result of a COVID-19 infection severe enough to need intensive care.

A new study published in the Clinical Kidney Journal this month looked at data from the Ontario Renal Network and found 271 people in 27 renal programs across the province who had contracted COVID-19 during the first two waves of the pandemic and developed an acute kidney injury that required renal replacement therapy (AKI-RRT).

The 271 patients all acquired COVID-19 between March 10, 2020 and January 31, 2021, accounting for nearly 10% of the province’s 2,490 COVID-19 ICU admissions during that time. As a consequence of a COVID-19, all had undergone acute renal replacement therapy (RRT).

The researchers discovered that 64 percent of the individuals identified, 174, had died 90 days after starting RRT, while 31% remained inpatient and 20% remained RRT-dependent.

“It was unexpected, but these are the most seriously sick folks.” Dr. Peter Blake, a researcher at Lawson and the provincial medical director of the Ontario Renal Network, stated, “Ninety-seven, 98 percent of them are in ICU, and 90 percent of them need ventilators because of the damage COVID has done to their lungs.”

“The current fatality rates for COVID patients admitted to ICU are about 25% to 30%.” This group is twice as large, indicating that they have COVID in a more severe form.”

According to Blake, there has been a lot of debate in “kidney doctor circles” about why COVID-19 might produce such a major renal problem, with one possibility being that the virus may infect the kidneys.

Important information for renal disease patients ?

Know what you’re up against.

People who have renal disease or other severe chronic medical diseases are at a greater risk of developing more serious illnesses.

Dialysis patients may have weakened immune systems, making it more difficult to fight infections. It’s vital to remember, however, that renal patients must continue with their regular dialysis treatments and take the required precautions as advised by their healthcare team.

Anti-rejection medications are required for those who have had a kidney transplant (also known as immunosuppressive medicines). These medications function by reducing the activity of the immune system, making it more difficult to fight infections. It is critical to continue taking these medications. It is also critical that they wash their hands, maintain excellent hygiene, and adhere to their healthcare team’s advice.

The investigation is still ongoing. ?

COVID-19 is a novel virus, thus research on it is only being started. Some hypotheses — ideas based on a small amount of evidence — about the effects of certain drugs on COVID-19 have been proposed, but nothing has been proven. In truth, prominent health agencies like as the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) have not advised people to cease using any specific medication in order to reduce their chances of contracting COVID-19 or make it less severe. The following are some commonly used medications that have recently been in the headlines.

Take the necessary safeguards. ?

COVID-19 sickness seems to be more severe in older persons and those with renal disease or other severe chronic medical problems. If you are at a greater risk of becoming severely ill as a result of COVID-19, you should take the following precautions:

Stock up on necessities.

Take daily efforts to maintain a safe distance between yourself and others.

When you’re out in public, stay away from ill people and avoid close contact.

Handwashing should be done often.

As much as possible, stay away from crowds.

Stay at home as much as possible if an epidemic occurs in your region. ?

Please keep in mind that if you are on dialysis, you must attend all of your appointments. If you are unwell or have any questions or concerns, contact your clinic.

It’s critical to remember to take your anti-rejection medications, maintain proper hygiene, and follow your healthcare team’s advice if you’ve had a kidney transplant. If you have any questions or concerns, please contact your healthcare provider.

With this NKF resource, you can learn more about how kidney patients can prepare for COVID-19.

Patients with COVID-19 are at a high risk of AKI. ?

AKI, which can lead to serious illness, dialysis, and even death, is a significant risk for people hospitalized with COVID-19, according to a new comprehensive report. Patients with COVID-19 who were admitted to the hospital between March 11 and April 26 were twice as likely to develop AKI as non-COVID patients who had AKI at the same period in 2019 – 56.9% against 25.1 percent, respectively. AKI seems to be a predictor of COVID-19 infection severity, and individuals with AKI have a greater fatality rate.

Kidney tubular injury (acute tubular necrosis) with septic shock, microinflammation, increased blood clotting, and possible direct infection of the kidney are all thought to be COVID-19-related effects that contribute to AKI. After recovering from COVID-19-related AKI, the majority of patients continue to have poor kidney function after being discharged from the hospital.

Acute kidney damage has long-term consequences. ?

COVID-19 individuals who have recovered from an AKI or ARF should consult a renal doctor on a frequent basis since their risk of developing chronic kidney disease is greater than others. Patients with COVID-19 who did not develop AKI but had blood and/or protein in their urine should be closely watched since they are at a higher risk of developing chronic and end-stage renal disease.

Kidney illness and the relationship ?

Acute kidney injury, also known as acute renal failure (ARF), is distinct from chronic kidney disease (CKD), which leads to chronic kidney failure (CKF). CKD and CKF are not reversible illnesses. In people with confirmed COVID-19, finding proteins and/or blood in urine labs is an early sign of kidney involvement.

In otherwise healthy persons, kidney failure occurs. ?

Acute kidney damage (AKI) – abrupt loss of renal function — has been reported in non-elderly persons who have been infected with COVID-19. There were no underlying medical issues in these people. AKI may be reversible with adequate treatment, which may include dialysis in severe instances.

Are there going to be any medicine shortages?

Because patients with kidney illness rely on medication to keep healthy, it’s critical to understand the problems surrounding possible drug shortages as a result of COVID-19. It’s difficult to predict which medications may be impacted, so don’t get too worked up. Hoarding and hoarding pharmaceuticals will only hasten the onset of drug shortages. If you are having trouble obtaining any of your medications, contact your healthcare practitioner.

You can order takeaway with confidence. ?

Many restaurants are now closed to maintain social distance, however many eateries still provide take-out. Here are some suggestions for making ordering takeout simple, even if you’re on a strict renal diet. Begin by becoming familiar with your diet and seeking assistance from your dietician. This information can assist you in making excellent selections based on your individual dietary requirements if you have sodium, potassium, phosphorus, or protein limits.

Prepare ahead of time.

Choose a place where you can easily choose items that are most suited to your diet. The best option is to go to a restaurant where the cuisine is prepared to order.

Choosing your options

Take a good look at the menu. Request additional information about issues you don’t understand. Explain that you are on a particular diet when placing your purchase. Make the following unique preferences for the way your meal is prepared:

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